LivingNeuralSystems

Brainif is the operating system for closed-loop biological neural experiments — design, simulate, replay, and analyze living neural systems.

Run the loop

See a closed loop, live.

Pick an input pattern and run the stimulation — watch the signal travel encoder → electrodes → synthetic activity → decoder → feedback.

SIMULATION MODEsynthetic activity · no biological data
Digital task
Input encoder
Electrode stimulation
Neural activity
Signal decoder
Feedback loop
Synthetic raster · 6 channels
Decoded output
Platform

A research control plane, end to end.

Everything from the experiment spec to the decoded result lives in one governed, reproducible pipeline — the same whether the activity is simulated or replayed.

Experiment design

Compose hypotheses, tasks, encodings and controls in a versioned, reproducible spec.

Electrode mapping

Assign input, output and feedback roles across a multi-electrode array.

Closed-loop feedback

Route decoded activity back into stimulation — open, closed, reinforcement or homeostatic.

Neural-data replay

Import recordings, map fields, and replay them through the same analysis pipeline.

Spike & burst analysis

Per-channel rates, burst detection, latency and stability from any run.

Condition comparison

Feedback vs. no-feedback, baseline vs. adaptation — side by side, descriptively.

Experiment lineage

Every result traces to its config version, simulator, decoder, seed and file hash.

Hardware adapter layer

A vendor-neutral interface ready for live MEA and remote biological-computing backends.

Three operating modes

Simulation. Replay. Live.

Every run is labeled with the mode that produced it — so a result is never mistaken for something it isn't.

SIMULATION

Simulation

Test experiment logic using synthetic neural activity.

Available now
RECORDED REPLAY

Replay

Import and analyze recorded biological data.

Available now
LIVE BIOLOGICAL

Live

Connect to supported laboratory or remote biological-computing systems.

Integration-ready · partner access required
Experiment studio

The instrument, not a dashboard.

Electrode map, live raster, decoder confidence and run metadata — all in one governed view.

exp_binary_classificationSIMULATION
running · trial 14/20
Electrode map · 8×8
input output feedback
Neural raster
Decoder confidence
Task
Binary classification
Encoding
spatial_stimulation
Decoder
firing_rate
Feedback
closed_loop
Seed
7
Synthetic activity. Validates software only — not evidence of biological learning.
Use cases

Built for the people who run the arrays.

01Biological computing research
02Neuropharmacology experiments
03Disease-model comparison
04Electrophysiology education
05Closed-loop neural stimulation research
06MEA workflow development
Scientific integrity

Honest by construction.

Brainif is a software platform and research control plane. It does not claim that simulated neurons are living neurons, and it never infers consciousness.

  • Simulated results are labeled clearly and validate software behaviour only.
  • Recorded biological data retains its source lineage and file hash.
  • Live experiments require approved hardware and laboratory access.
  • Brainif does not infer consciousness or make clinical claims.
  • Results require appropriate controls and expert interpretation.
Developers

Experiments as an API.

Every experiment is a versioned object. Define it in the studio or POST it directly — the same governed pipeline runs either way.

brainif · REST
POST /api/experiments
{
  "name": "Binary signal classification",
  "mode": "simulation",
  "inputEncoding": "spatial_stimulation",
  "decoder": "firing_rate",
  "feedbackProtocol": "closed_loop"
}
Part of the Brainif software platform.

Bring your neural recordings or MEA workflow.

Replay a dataset, design a protocol, or talk to us about connecting live hardware.